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The concomitant use of tramadol hydrochloride tablets and CYP3A4 inducers can lower the plasma concentration of tramadol[see Scientific Pharmacology (twelve.3)], causing lowered efficacy or onset of the withdrawal syndrome in patients who've made Bodily dependence to tramadol.The concomitant usage of tramadol hydrochloride tablets and CYP3A4 inhibi

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